Efficacy of using PDGF and xenograft with or without collagen membrane for bone regeneration around immediate implants with induced dehiscence-type defects: a microcomputed tomographic study in dogs.

نویسندگان

  • Bann Ahmad Al-Hazmi
  • Khalid Saleh Al-Hamdan
  • Abdulaziz Al-Rasheed
  • Nadir Babay
  • Hom-Lay Wang
  • Khalid Al-Hezaimi
چکیده

BACKGROUND Use of collagen membrane (CM) with xenograft and recombinant human platelet-derived growth factor (rhPDGF) in guided bone regeneration (GBR) is debatable. The aim of this microcomputed tomographic experiment was to assess the efficacy of using PDGF and xenograft (with or without CM) for GBR around immediate implants with dehiscence defects. METHODS Ten beagle dogs underwent atraumatic bilateral second and fourth premolar extractions from both arches. A standardized dehiscence defect (6 × 3 mm) was created on the buccal bone and immediate implants were placed in distal sockets in each site. Animals were randomly divided into three groups: 1) group 1, xenograft with rhPDGF was placed and covered with CM; 2) group 2, xenograft with rhPDGF was placed over the defects; and 3) group 3, four immediate implants were associated with dehiscence (controls). After 16 weeks, animals were sacrificed and jaw segments were assessed for buccal bone thickness (BBT), buccal bone volume (BBV), vertical bone height (VBH), and bone-to-implant contact (BIC) using microcomputed tomography. RESULTS BBT was higher in group 2 (1.533 ± 0.89 mm) than group 1 (0.745 ± 0.322 mm) (P <0.001) and group 3 (0.257 ± 0.232 mm) (P <0.05). BBV was higher in group 2 (67.87 ± 19.83 mm(3)) than group 1 (42.47 ± 6.78 mm(3)) (P <0.05) and group 3 (19.12 ± 4.06 mm(3)) (P <0.001). VBH was higher in group 2 (6.36 ± 1.37 mm) than group 3 (0.00 ± 0.00 mm) (P <0.001). VBH was higher in group 1 (3.91 ± 2.68 mm) than group 3 (0.00 ± 0.00 mm) (P <0.05). BIC was higher in group 2 (67.25% ± 13.42%) than group 1 (36.25% ± 12.78%) (P <0.05) and group 3 (30.25% ± 7.27%) (P <0.01). CONCLUSION GBR around immediate implants with dehiscence defects using PDGF and xenograft alone resulted in higher BBT, BBV, VBH, and BIC than when performed in combination with CM.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Effect Of Restoration Type On Osseointegration of Dental Implants: A Histological Analysis In Dogs

  Background and Objective: The concept of immediate occlusal loading with dental implants offers several advantages. In this research, the effect of type of restoration on Osseointegration rate of dental implants was histologically evaluated. Materials and Methods: Three months prior to implantation, the lower premolar teeth of 15 dogs were extracted. Then, 3 to 4 Maestro™ implants were plac...

متن کامل

Comparative analysis of collagen membranes for the treatment of implant dehiscence defects.

Guided bone regeneration (GBR) evolved from the concept of guided tissue regeneration (GTR) and has been used for reconstructing sites with bone deficiencies associated with dental implants. For GBR, the use of absorbable collagen membranes has been increasing, but, at present, scientific information on the use of collagen membranes for GBR is limited. This study was aimed to clinically and his...

متن کامل

A Comparision of Two Types of Decalcified Freeze-Dried Bone Allograft in Treatment of Dehiscence Defects around Implants in Dogs

BACKGROUND Decalcified freeze-dried bone allograft (DFDBA) may have the potential to enhance bone formation around dental implants. Our aim in this study was the evaluation and comparison of two types of DFDBA in treatment of dehiscence defects around Euroteknika(®) implants in dogs. METHODS In this prospective clinical trial animal study, all mandibular premolars of three Iranian dogs were e...

متن کامل

مقایسه بالینی روش بازسازی هدایت شده بافتی (GTR) به وسیله غشا کلاژنه و پیوند استخوان، با روش پیوند نسج همبندی در درمان تحلیلهای لثه

Background and Aim: Increasing patient demands for esthetic, put the root coverage procedures in particular attention. Periodontal regeneration with GTR based root coverage methods is the most common treatment used. The purpose of this study was to compare guided tissue regeneration (GTR) with collagen membrane and a bone graft, with sub-epithelial connective tissue graft (SCTG), in treatment o...

متن کامل

Microcomputed tomographic analysis of the alveolar ridge alteration around extraction sites with and without immediate implants placement: in vivo study.

BACKGROUND The aim was to assess the alveolar ridge alteration around extraction sites with and without immediate implants according to extraction socket classification (ESC) using microcomputed tomography (micro-CT). MATERIAL AND METHODS Ten beagle dogs (mean age and weight: 24 ± 0.83 months and 13.8 ± 0.49 kg, respectively) were randomly divided into three groups according to the ESC. In Gr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Journal of periodontology

دوره 84 3  شماره 

صفحات  -

تاریخ انتشار 2013